José Guillén became one of the most prominent players linked to baseball's performance-enhancing-drug era. His name appeared in the Mitchell Report, which investigated steroid and human-growth-hormone distribution around Major League Baseball, and reports said that performance-enhancing drugs had been sent directly to him at the Oakland Coliseum in 2003. Guillén denied using or even being offered such substances, but in 2009 he acknowledged that he had worked for years with Angel Presinal, a personal trainer closely associated with performance-enhancing drugs and barred from major-league clubhouses. Guillén said he had stopped working with Presinal in 2004, although the two remained friends. MLB initially suspended Guillén for 15 games after he signed with Kansas City, but that punishment was rescinded in April 2008 when baseball and the players' union modified the drug-testing agreement and granted amnesty to players named in the Mitchell Report. The controversy returned in 2010 after Guillén joined the San Francisco Giants: MLB investigated shipments of human growth hormone connected to him and ordered the club to keep him off its postseason roster. On November 14, 2010, it was reported that the Drug Enforcement Administration had intercepted a package containing 50 HGH syringes en route to Guillén's home. The investigation and intercepted shipment produced severe reputational and postseason consequences, but the available account does not establish that Guillén was criminally convicted or that he admitted to using HGH.
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