The lasting cost of the Márquez–Vázquez rivalry was concentrated in the damage to Vázquez’s eyes. During the third fight, Vázquez fought through deep cuts around both eyes and absorbed twelve rounds of punishment before winning a disputed split decision. The injuries were not merely cosmetic: he required three surgeries to repair a damaged retina and remained out of the ring for more than a year. When he returned in October 2009 against Angel Antonio Priolo, he struggled to a ninth-round victory, a sharp contrast to the explosive champion who had once stopped Oscar Larios and Jhonny González.
The fourth meeting in May 2010 was held without a title because Vázquez’s inactivity had led to his being stripped of the championship. Márquez exploited the impaired vision immediately, cutting Vázquez over the left eye in the second round and over the right in the third. Vázquez was knocked down by a right hand early in the third and, unable to see clearly, was stopped after taking a further series of heavy punches. Although both fighters initially expressed interest in a fifth bout, Vázquez’s longtime handler Frank Espinoza bluntly declared, “His career is over,” an assessment echoed by boxing writers who regarded another fight as medically reckless. Vázquez retired after the fourth contest, while Márquez continued until 2013; the rivalry’s celebrated action therefore ended as a career-altering medical cautionary tale rather than with a fifth chapter.
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